Clinical research on nutritional formula helps children increase resistance, improve weight and height



Effectiveness of supplementing ColosCare powdered milk on the nutritional status and health of preschool children


Nutrition for children, especially in rural areas of Vietnam, is also a national health issue affecting the stature, height, intelligence and working capacity of Vietnamese people, a special interest to the health sector and the Government [1]. One of the effective measures is to use milk supplemented with nutrients and micronutrients for young children [2], [3]. Adding micronutrients to drinking milk has been a medium-term, effective and sustainable solution to eliminate the shortage of micronutrients, contributing to reducing malnutrition rates in children in Vietnam in particular and around the world in general. These solutions are implemented through micronutrient supplementation campaigns, or by products supplemented with micronutrients and minerals [4], [5].

However, the balanced and appropriate composition and content of supplemented milk is still an issue to be researched.

ColosCare 2+ formula nutritional product (in short: ColosCare 2+ Powdered Milk) is produced by Nutricare Nutrition Joint Stock Company, for children from 2-10 years old, enables strong immune and weight gain. ColosCare 2+ contains important nutrients, optimal for weight gain and strengthening the child’s immune system: Colostrum is highly biologically active with IgG 1200+ antibody content, DHA, Iodine, Folic acid, trio of nutrients HMO, Lactoferrin & Beta-Glucan,…

To evaluate the effectiveness of the ColosCare 2+ product on nutritional status and health in children, Nutricare coordinated with Thai Binh University of Medicine and Pharmacy to conduct a clinical trial study “Effectiveness of ColosCare powdered milk supplementation”. on the nutritional status and health of preschool children”. The study was approved by the Ethics Committee of Thai Binh University of Medicine and Pharmacy.

Research subjects

The study was conducted on preschool children (36-59 months old) in 02 kindergartens in Kien Xuong district, Thai Binh province..

 Selection criteria: children attend school; without birth defects, mental or motor disabilities or children with chronic diseases; consent from parents/guardians.

– Exclusion criteria: sick; overweight, obesity; using nutritional supplements, participating in other research.

Research period

The study was conducted from October 2021 to October 2022.

Research product

Formula nutritional product for children 2-10 years old ColosCare 2+ (in short: ColosCare 2+ powdered milk) – Strong resistance, weight gain, researched and produced by Nutricare Nutrition Joint Stock Company. The product contains highly biologically active Colostrum with exceptionally high levels of IgG 1200+ antibodies, helping to strengthen children’s natural resistance.

In addition, ColosCare 2+ also adds the trio of nutrients HMO, Lactoferrin & Beta-Glucan to help reduce infections in children, limit the invasion of disease-causing bacteria and viruses, and improve respiratory and digestive health; The duo of fiber and probiotics supports children’s intestinal health and digestive system. DHA and Iodine in ColosCare 2+ help children develop their brains, Taurine protects vision, and Folic Acid optimizes the learning, memory, and cognitive processes in children..

Research results

A randomized controlled clinical trial study on preschool children (36 – 59 months old) during 2 months of intervention showed that:

ColosCare 2+ Powdered Milk supplemented for preschool children has had a positive impact on nutritional status and health with high acceptability.:

– Weight improvement: the average weight gain was 0.41 kg higher (0.68 ± 0.10 kg vs. 0.27 ± 0.08 kg) which was statistically significant (p<0,05)

 Height increase: The mean height gain was 0.35 cm higher (1.45 ± 0.11 cm vs. 1.10 ± 0.16 cm) which was statistically significant (p<0,05)

– Tends to increase resistance, reducing respiratory infections, diarrhea, constipation, anorexia, and difficulty sleeping, however the study range was small and the study period was short, which is not statistical significant.

– High acceptability of use: the rate of drinking milk is 97.8%, of which the rate of drinking sufficient milk is 91.6% with 2 times/day.

With this research result, ColoCare Powdered Milk is the smart choice to help children increase their immune health, gain weight steadily, and dispel worries about illness and weakness in children compared to their peers.

The study was published in the Vietnam Medical Journal, published by the Vietnam Medical Association, issue 1 – January 2023.



  1. Chính phủ (2015). Chiến lược quốc gia về dinh dưỡng giai đoạn 2011 – 2020 và tầm nhìn đến năm 2030.  
  2. Chính phủ (2016). Chương trình sữa học đường cải thiện tình trạng dinh dưỡng góp phần nâng cao tầm vóc trẻ em mẫu giáo và tiểu học đến năm 2020.  
  3. Best C., Neufingerl N., Del Rosso J.M., et al.  (2011). Can multi-micronutrient food fortification improve the micronutrient status, growth, health, and cognition of schoolchildren? a systematic review. Nutr Rev, 69(4), 186–204. 
  4. World Health Organization (2013). Essential Nutrition Actions: improving maternal, newborn, infant and young child health and nutrition.
  5. World Health Organization (2007). The new WHO child growth standards. Bull World Health Organ, 52(1), 13-17.
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